When a scientific question requires a tool that hasn't been built, we build it. Our platforms are actively used in IRB-approved clinical studies at WVU.
SeizEAR is an in-ear EEG system that captures brain electrical signals through electrodes embedded in a custom ear canal mold — housed within a commercial hearing aid form factor. The external auditory canal provides a biologically shielded, mechanically stable recording site with surprisingly strong signal quality for interictal epileptiform discharge detection.
Unlike scalp EEG, SeizEAR is designed for continuous ambulatory use over days to weeks — capturing the brain's electrical activity during everyday life. This opens new possibilities for naturalistic epilepsy monitoring, medication efficacy tracking, and passive biomarker acquisition in neurodegenerative disease.
The Axon-R platform is built on the Cognixion ONE augmented reality headset — a purpose-built assistive technology device that combines gaze-tracking, EEG, and spatial computing. We integrate this hardware with real-time EEG signal processing and neural decoding to create a communication and language rehabilitation interface for patients with expressive aphasia.
Pursued through the NSF BRAIN Pilot IUCRC grant with the Aphasia sub-study (SS-01), the Axon-R system enables patients who have lost the ability to speak — due to stroke, epilepsy surgery, or neurodegenerative disease — to communicate using neural signals combined with AR-assisted word and concept selection.
The foundation of our human electrophysiology research is a well-established clinical research infrastructure embedded in the WVU Epilepsy Monitoring Unit. Patients undergoing stereoEEG evaluation for epilepsy surgery have 10–20 depth electrodes implanted across lateral and medial temporal, frontal, cingulate, and insular targets — providing simultaneous broadband access to distributed circuits.
We have built a research pipeline around this clinical program: IRB-approved protocols for task-based paradigms during EMU admission, custom signal processing toolboxes for spectral analysis and phase-amplitude coupling, and a growing database of research-quality intracranial EEG from adult and pediatric patients. Our system supports parallel broadband (1–10,000 Hz) recording alongside the clinical EEG system.
The next generation of Chan Lab technologies — currently in early development or planning stages.
We collaborate closely with industry and academic partners to translate laboratory prototypes into tools ready for clinical research.